Breaking News, Trials & Filings

InterMune Stops Phase III IPF Actimmune Trial

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By: Tim Wright

Editor-in-Chief, Contract Pharma

InterMune, Inc. has discontinued the Phase III INSPIRE trial evaluating Actimmune in patients with idiopathic pulmonary fibrosis (IPF) based on the recommendation of an independent data monitoring committee (DMC). Interim analysis included a total of 115 deaths and the DMC found the overall survival result crossed a predefined stopping point for lack of benefit of Actimmune relative to placebo. There wasn’t a statistically significant difference between treatment groups in overall mortalit...

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